June 2-5, Moscow, Russia

Russian International Сonference on cryoelectron microscopy 2019

Organizer: Lomonosov Moscow State University

RICCEM-2019

The Second Russian international conference “Cryo-electron microscopy 2019: achievements and prospects” will be held at Lomonosov Moscow State University (MSU) on June 2 – 5, 2019.

The main purpose of this conference is to inform the Russian scientific community of the technical progress attained in structural biology and of the latest achievements in the field of cryo-electron microscopy. This event will become a communication platform between internationally recognized experts and young researchers in the rapidly developing region of cryo-electron microscopy. Leading researchers from Russia, Europe and the USA will take part in this conference; this will undoubtedly have a positive effect on the international reputation of Moscow State University. The conference will have a significant impact on the further advancement of cryo-EM in Russia and the implementation of the most modern structural methods at MSU; it will also establish fruitful partnerships between researchers in Russia and abroad.

Recent advances in deciphering the atomic structure of macromolecules using cryo-electron microscopy and various aspects of sample preparation will be discussed at the conference.

Looking forward to meeting you at MSU!

Workshops will be held on the topics of:

Membrane proteins and the methods of studying their structure;

Structure and functions of the transcription and translation apparatus of the cell;

Structure of viruses and chaperonins;

Molecular organization of cells and organelles; tomography

New methods of sample preparation and data processing for cryo-electron microscopy;

Applications for medicine

Announcements

Book of Abstracts

The Abstract Book of RICCEM-2019 is now available for download

Photos

Organising Committee

Mikhail P. Kirpichnikov, member of the Russian academy of sciences, Prof., Dean of the Faculty of Biology, MSU

Vladimir P. Skulachev, member of the Russian academy of sciences, Prof., Director of the Belozersky Institute of Physico-Chemical Biology, MSU

Member of RAS O.Dontsova, corr. member of RAS V.Popov, Prof. K.Shaitan, Prof. V.Gordeliy, Dr. I.Alieva, Dr. A.Vasilyev

Prof. of RAS O.Sokolova, Dr. I.Kireev

Program Committee

Prof of RAS Olga Sokolova, Prof. Elena Orlova, Prof. Alexander Sobolevsky, Dr. Valentin Gordeliy, Dr. Alexander Vasiliev, Dr. Igor Kireev

Conference Schedule

Program

From 10-00Bld. 12

Start of on-site registration at the Faculty of Biology

1 Leninskie Gory, Bld. 12. Big Biological Auditorium
14:00

Conference opening. Greeting from deputy vice-rector of Moscow State University, Prof. Piotr Kamenski

Section I: Structure of membrane proteins

14:15
Yifan Cheng
Yifan Cheng

UCSF

Single particle cryo-EM of membrane proteins

15:00
Alexander Sobolevsky
Alexander Sobolevsky

Columbia University

Structural and functional studies of vanilloid subtype TRP channels

15:45
Misha Kudryashev
Misha Kudryashev

MPI for Biophysics and BMLS/ Unviersity of Frankfurt, Germany

Structure of ion channels in membranes

16:30
Zakhar Shenkarev
Zakhar Shenkarev

Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry

NMR spectroscopy: alternative method for structural studies of highly dynamic membrane proteins and ion channels

17:00
Dirk Slotboom
Dirk Slotboom

University of Groningen, Netherlands

Structural and mechanistic diversity of vitamin B12 transporters

18:00

Welcome party at the MSU botanical garden

Section II: Structure and functions of the transcription and translation apparatus of the cell

9:00
Guillermo Montoya
Guillermo Montoya

CryoEM analysis unveils the conformational activation of CRISPR-Cas12a and endonuclease activity resetting

9:45
Yury Polikanov
Yury Polikanov

University of Illinois at Chicago

Recent advances in structural studies of bacterial ribosome using X-ray crystallography and cryo-electron microscopy

10:15
Mario Halic
Mario Halic

St. Jude Children’s Research Hospital, Memphis, TN

Cryo-EM structures of chromatin complexes

10:45
Andrey Konevega
Andrey Konevega

NRC "Kurchatov Institute" - PNPI

Molecular mechanism of antibiotics inhibiting prokaryotic translation

11:15

Group Photo

11:30

Coffee-break

12:00
Svetlana Dodonova
Svetlana Dodonova

Max Plank Institute for Biophysical Chemistry

Investigating interaction of pioneering transcription factors with nucleosomes using cryo-EM

12:30
Ilya Osterman
Ilya Osterman

MSU

Mechanism-driven antibiotic discovery: combination of biochemical and structural approaches

13:00
Dmitry Zharkov
Dmitry Zharkov

Novosibirsk State University

Fleeting ensembles: transient protein-protein interactions in DNA repair

13:15
Egor Svidritskiy
Egor Svidritskiy

University of Massachusetts Medical School

Dissecting the dynamics of translation termination by ensemble cryo-EM

14:15
Vasily Kuvichkin
Vasily Kuvichkin

Institute of Cell Biophysics of the Russian Academy of Sciences

Investigation by Cryo-TEM in vitro of ternary complexes: zwitterionic liposomes, DNA, Mg++ show first stage of nuclear pores assembly

14:30

Lunch

16:00

Round table «Cryoelectronic microscopy and the prospects of implementing its results in pharmacology and personalized medicine»

The participation of academic and university scientists, representatives of pharmaceutical companies, microscope and microscopy equipment manufacturers is anticipated. 
16:45

Coffee-break

17:00

Poster session

Section III: Molecular organization of cells and organelles

9:00
Kushal Sejwal
Kushal Sejwal

High-resolution structures of microtubule-drug complexes revealed by cryo-EM

9:45
Yurii Krupyanskii
Yurii Krupyanskii

Semenov Institute of Chemical Physics RAS

Сondensation of nucleoid in bacteria as a result of starvation

10:15
Galina Beznoussenko
Galina Beznoussenko

IFOM

Immunolabeling of cryo-slices in combination with correlative light and electron microscopy

10:45
Igor Kireev
Igor Kireev

Looking for an order in chaos: approaches to mapping chromosomal loci for cryo-EM studies

11:15
Karlen Hovnanyan

Select Scientific Technological Center of Organic and Pharmaceutical Chemistry of NAS RA

Cryo-ultramicrotomy for ultrastructural analysis of some prokaryotes and eukaryotes

11:30
Piotr Wardega
Piotr Wardega

High resolution protein structure stability analysis using nanoDSF technology

11:45

Coffee-break

Section IV: Structure of viruses and chaperonins

12:15
Matthias Wolf
Matthias Wolf

Okinawa Institute of Science and Technology Graduate University, Japan

Cryo-EM Structure of the Ebolavirus Nucleoprotein RNA complex

13:00
Victor Kostyuchenko
Victor Kostyuchenko

Duke-NUS Medical School

Cryo-microscopy of flaviviruses: what we can learn with a good microscope.

13:30
Natalia Plekhova
Natalia Plekhova

Pacific State Medical University

Entry of Hantavirus into the innate immunity cell

13:55
Tatiana Stanishneva-Konovalova
Tatiana Stanishneva-Konovalova

Asymmetric structure of OBP chaperonin

14:25
Liya Mukhamedova
Liya Mukhamedova

CEITEC, Brno, Czech Republic

The structure of human Echovirus 30

14:45

Lunch

15:45

Moscow sightseeing bus tour

19:30

Social event at the observation desk on the 89th floor of the Federation tower in «Moscow City»

Section V: Applications of cryo-EM in medicine

9:00
Alexis Rohou
Alexis Rohou

Supporting drug discovery with cryoEM

9:45
Gunnar Schreuder
Gunnar Schreuder

Institute of Complex Systems (ICS-6) / Forschungszentrum Jülich, Germany

Fibril structure and interface polymorphism of amyloid-ß(1-42)

10:15
Albert Guskov
Albert Guskov

University of Groningen, Netherlands

Functional and structural studies on human ASCT2 transporter — a promising drug target

10:45
Konstantin Usachev
Konstantin Usachev

Structural and functional studies of the staphylococcus aureus ribosome hibernation

11:00
Pavel Afanasyev
Pavel Afanasyev

Cryo-EM of Human and Parasite Proteasomes for Structure-Based Drug Design

11:30

Coffee-break

Section VI: New methods of sample preparation and data processing for cryo-electron microscopy

12:00
Thorsten Wagner
Thorsten Wagner

Max Planck Institute of Molecular Physiology

Automated particle picking and preprocessing in SPHIRE

12:30
Elena Orlova
Elena Orlova

Birkbeck College

High resolution studies of biocomplexes by cryo-electron microscopy, basis for high throughput studies

13:10
Berend Lich
Berend Lich

Recent developments in Cryo-EM

13:30
Alexander Myasnikov
Alexander Myasnikov

High resolution cryo-electron microscopy and new direct electron detector from Gatan — K3

14:15
Grigory Armeev
Grigory Armeev

Integrative approach on nucleosome complexes modelling

14:30

Lunch

Section VII: Complex and emerging techniques in structural biology

15:30
Aleksandr Kudriavtsev
Aleksandr Kudriavtsev

Lomonosov Moscow State University / Emanuel Institute of Biochemical Physics

Current status of biomolecules imaging by X-ray Free Electron Laser without crystallization

15:45
Dmitry Bagrov
Dmitry Bagrov

Faculty of Biology, Lomonosov Moscow State University

Visualization of exosomes using transmission electron microscopy and immunogold labelling

16:00
Dina Schneidman
Dina Schneidman

Fitting structural fragments into electron microscopy density maps using spectral shape descriptors

16:20
Konstantin Boyko
Konstantin Boyko

3D structure of natural tetrameric form of human butyrylcholinesterase obtained by CryoEM, MD and SAXS methods

16:40

Coffee-break

17:00
Igor Nikishin
Igor Nikishin

Detection and Characterization of Extracellular Vesicles in Transmission Electron Microscopy by Convolutional Neural Network

17:15
Roman Kamyshinsky
Roman Kamyshinsky

NRC Kurchatov Institute

In vitro Cryo Electron Tomography study of protective Dps-DNA co-crystallization

17:30

Best poster and best young speaker award (sponsored by Crystals — Open Access Journal)

17:45

Concluding remarks from Dean of Biology department, academician, Prof. Mikhail Kirpichnikov

18:00

Conference closing

Conference Venue

The conference was successfully held at Moscow State University, Faculty of Biology, the BBA auditorium (Address: 1 Leninskie gory, Bldg. 12)

Sponsors

Media partners